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目的观察小儿病毒性心肌炎应用果糖二磷酸钠与磷酸肌酸钠治疗对患儿免疫功能及治疗效果的影响。方法选取我院2015年10月至2016年10月治疗的88例病毒性心肌炎患儿的临床资料,根据治疗方案的不同将其分为两组,将单纯予果糖二磷酸钠治疗的设为对照组(41例),将联合磷酸肌酸钠治疗的设为研究组(47例),比较两组免疫功能及治疗效果。结果两组治疗后LDH与CK水平较之治疗前均降低,且研究组降低幅度较之对照组更大(P<0.05);研究组总有效率比对照组低(P<0.05)。结论果糖二磷酸钠联合磷酸肌酸钠治疗病毒性心肌炎患儿可有效改善其免疫功能,并提高临床疗效,具广泛应用价值。
Objective To observe the effect of application of sodium fructose diphosphate and sodium creatine phosphate on immune function and therapeutic effect in children with viral myocarditis. Methods The clinical data of 88 children with viral myocarditis treated in our hospital from October 2015 to October 2016 were selected and divided into two groups according to the different treatment regimens. The treatment of simple fructose diphosphate was used as control Group (n = 41). The treatment group (n = 47) was treated with sodium creatine phosphate. The immune function and therapeutic effect were compared between the two groups. Results After treatment, the levels of LDH and CK in both groups were lower than those before treatment, and the reduction rate in the study group was greater than that in the control group (P <0.05). The total effective rate in the study group was lower than that in the control group (P <0.05). Conclusion Fructose sodium phosphate combined with creatine sodium in children with viral myocarditis can effectively improve their immune function and improve clinical efficacy, with a wide range of applications.