我们报道一例由多变根毛毒引起的原发性、慢性、破坏性粘膜皮肤毛霉病。患者女，５４岁，河北省定州农民。因面部皮损缓慢扩展１６年，进行性破溃１个月，于１９９２年４月２７日就诊。１６年前无明显诱因左颊部出现局限性红斑，不痒，随后皮损缓慢向周围扩大，略高起皮面。４ We report, for example, a case of primary, chronic, damaging mucocutaneous mucormycosis caused by genital fever. Female patient, 54 years old, farmers in Dingzhou, Hebei Province. Due to the slow expansion of facial skin lesions for 16 years, progressive rupture for 1 month, on April 27, 1992 treatment. 16 years ago, there was no obvious incentive to appear limitations of the left cheek erythema, itch, then the lesion slowly expanded to the surrounding, slightly higher skin. 4