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目的:探讨急性脑梗塞采用奥扎格雷钠治疗的临床效果。方法:本次研究选择的对象共120例,均为我院2009年2月至2012年2月收治的急性脑梗塞患者,随机按观察组和对照组各60例划分,对照组采用降压、抗血小板聚集、血脂调节等常规治疗,观察组在应用常规方案的同时,加用奥扎格雷钠治疗,回顾两组临床资料。结果:两组神经功能缺损评分在治疗前无明显差异(P>0.05),治疗后均有下降,但观察组下降幅度显著优于对照组,差异有统计学意义(P<0.05)。观察组60例患者中,总有效率为96.7%,对照组60例患者中,总有效率为80%,观察组临床总有效率显著高于对照组,差异有统计学意义(P<0.05)。两组肝功能、出凝血时间、血小板在治疗前后经实验室检查无明显变化。结论:急性脑梗塞采用奥扎格雷钠治疗,可促使神经功能最大程度的恢复,提高临床总有效率,消除临床症状,改善预后,对提高患者的生存质量有非常重要的意义,值得临床广泛开展应用。
Objective: To investigate the clinical effect of sodium ozagrel treatment in acute cerebral infarction. Methods: A total of 120 subjects were selected in this study, all of whom were acute cerebral infarction patients admitted from February 2009 to February 2012 in our hospital. Each group was randomly divided into observation group (60 cases) and control group (60 cases) Anti-platelet aggregation, blood lipid regulation and other conventional treatment, the observation group in the application of conventional programs at the same time, plus sodium ozagrel treatment, review the two sets of clinical data. Results: There was no significant difference in the score of neurological deficit between the two groups before treatment (P> 0.05), but both of them decreased after treatment. However, the decline rate of the observation group was significantly better than that of the control group (P <0.05). The total effective rate was 96.7% in the 60 patients in the observation group and 80% in the 60 patients in the control group. The total effective rate in the observation group was significantly higher than that in the control group (P <0.05) . Two groups of liver function, a clotting time, platelets in the treatment before and after no significant change by laboratory tests. Conclusion: The treatment of acute cerebral infarction with ozagrel sodium can promote the maximal recovery of nerve function, improve the total effective rate, eliminate the clinical symptoms and improve the prognosis, which is of great significance to improve the quality of life of patients and deserves extensive clinical development application.