TrKB相关论文
目的 探讨ANA-12靶向抑制脑源性神经营养因子（BDNF）/酪氨酸激酶受体B（TrkB）信号缓解奥沙利铂（OXA）化疗痛的作用及机制。方法 将18只雄性S......
目的:7.8-二羟基黄酮在多种帕金森动物或细胞模型中都表现出显著的保护性作用。本实验室既往研究表明7.8-二羟基黄酮可以减少帕金......
背景:神经退行性疾病是以神经元进行性丧失为特征的疾病,包括肌萎缩性侧索硬化（Amyotrophic lateral sclerosis,ALS）,阿尔茨海默病（Al......
空间学习与记忆是动物在适应性进化过程中形成的重要行为之一,它可以影响动物对自身行为的决策。较强的学习记忆能力可使动物降低......
目的:研究磷酸三苯酯（TPHP）暴露对大鼠的焦虑和抑郁样神经毒性作用及其作用机制。方法:雄性和雌性SD大鼠各52只,随机分为4组,分别为......
目的 探讨干扰长链非编码RNA(LncRNA)NEAT1表达对1-甲基-4苯基-吡啶离子(MPP+)诱导的人神经母细胞瘤细胞SH-SY5Y中脑源性神经营养......
目的观察补中益气安神汤（BZYQAS）对脾虚证失眠脑肠轴CREB/BDNF/TrkB信号通路的影响。方法将大鼠随机分为8组:正常组,模型组,百乐眠组......
目的:既往研究显示,BDNF（Brain derived neurotrophic factor,脑源性神经营养因子）与其高亲和力受体TrkB（Tropomyosin related kinase......
目的 通过观察电针“四关”穴及其相应单穴对脑卒中后抑郁(post-stroke depression,PSD)大鼠行为学及海马神经脑源性神经营养因子(......
BDNF-TrkB signaling pathway is involved in pentylenetetrazoleevoked progression of epileptiform acti
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Melatonin Augments the Effects of Fluoxetine on Depression-Like Behavior and Hippocampal BDNF-TrkB S
Depression is a debilitating psychiatric disorder with a huge socioeconomic burden,and its treatment relies on antidepre......
目的：观察电针心经原穴及其配穴对心肌缺血大鼠海马BDNF、TrkB蛋白及mRNA表达的影响,探讨针刺抗心肌缺血脑损伤的保护作用及部分机......
BDNF-TrkB signaling mediates ubiquitin-proteasome-dependent homeostatic regulation of synaptic prote
Homeostatic regulation of synaptic properties in response to chronic alteration of neuronal activity is essential for ne......
Huntingtons disease (HD) is an autosomal dominant hereditary disease caused by a trinucleotide repeat mutation in the hu......
Protective effects of Buyang Huanwu Decoction on axotomized rubrospinal neurons after spinal cord in
Objective To observe the effect ofBuyang Huanwu Decoction (BYHWD) on neuron protection.Methods SD rats were given BYHWD ......
Long-range anterograde transport of tropomyosin receptor kinase B (TrkB) in axons is important for exerting appropriate ......
Tropomyocin receptor kinase B amends central cardiovascular regulatory dysfunction induced by mevinp
Aim: This presentation investigates the role of tropomyocin receptor kinase B (TrkB), which is the receptor for brain-de......
Antidepressant effect of Xiaochaihutang in the unpredictable chronic mild stress model via increasin
Aim: Xiaochaihutang (XCHT) has been used in China for thousands of years to treat "Shaoyang syndrome", which involves ......
会议
Two Standardized Fractions of Gardenia Jasminoides with Rapid Antidepressant Effects Are Differentia
As conventional antidepressants have a major disadvantage in weeks-long delay of therapeutic effects.Novel antidepressan......
Brain-derived neurotrophic factor (BDNF) is known to be crucial for synaptic development and plasticity in the central n......
BDNF Mediated TrkB Activation Contributes to The EMT Progression in Human Salivary Adenoid Cystic Ca
Purpose: Brain-derived neurotrophic factor(BDNF)and its receptor Tropomysin-related kinase B(TrkB)are over-expressed in ......
黄蜀葵花(Abelmoschus manihot (L.) Medic.)为中国民间草药,属于黄秋葵属锦葵科,已报道其具有抗抑郁活性.本文从黄蜀葵花中分离纯......
Effect of early thyroxine treatment on the development of Purkinje cells in fetal alcohol-exposed ra
This study was designed to investigate the effect of early thyroxine (T4) treatment on the development of the Purkinje c......
Synaptic loss in the brain correlates well with disease severity in Alzheimer disease (AD).Deficits in brain-derived neu......
目的 观察锌和叶酸联合补充对抑郁症的的影响并探讨其作用机制.方法 雄性SD 大鼠随机分为5组：对照组(C,9只)、模型组(M,12只)、帕罗......
Transient exposure to echinacoside is sufficient to activate Trk signaling and protect neuronal cell
Neurotrophins exert their physiological functions mainly through Trk receptors, and the neurotrophic signaling network i......
目的：多项研究结果表明，前额叶皮层(PFC)的结构和功能在抑郁症中发生了改变，如神经病理学实验表明，在抑郁症病人的前额叶处，神经元的数......
目的 观察成年中缅树鼩大脑BDNF、trkB、ChAT mRNA及蛋白的表达.方法 利用qPCR和western blotting方法检测成年中缅树鼩大脑海马、......
目的评价七氟醚防治小鼠抑郁样行为的效果及其与脑源性神经营养因子(BDNF)/酪氨酸激酶B(TrkB)信号通路的关系。方法清洁级雄性C57B......
目的观察脑源性神经营养因子(BDNF)及其受体酪氨酸激酶B(TrkB)在慢性应激大鼠结肠动力紊乱中的作用及其机制。方法将20只Wistar雄......
目的探讨酪氨酸激酶受体B（tyrosine kinase receptor B，TrkB）对鼻咽癌细胞系C666-1失巢凋亡特性的影响和调控。方法用反转录聚合酶链......
目的:探讨红景天苷对缺氧复氧神经元细胞活力、凋亡及BDNF/TrkB信号转导通路的影响.方法:设人类皮质神经元(CNC)组、缺氧复氧组、......
HPV16 E6 gene mutation promotes the proliferation of cervical cancer cells by regulating the express
Objective:Study on the mechanism of HPV16 E6 gene mutation promoting the proliferation of cervical cancer cells by influ......
Immunohistochemical study on distribution of endocrine cells in gastrointestinal tract of flower fis
AIM: To detect distribution and relative frequency of endocrine cells in gastrointestinal tract of flower fish (Pseudoph......
目的探讨微波辐射对大鼠大脑皮层和海马突触素Ⅰ及其相关影响因子BDNF和受体TrkB表达的影响。方法采用30mW／cm^2微波辐射Wistar雄性......
目的:研究来曲唑(LE)诱导的多囊卵巢综合征(PCOS)大鼠模型卵巢组织中脑源性神经营养因子(BDNF)及其受体——TrkB蛋白的表达及对卵......
脑来源的神经营养因子表达和Ｐ１４５~（ＴｒＫＢ）对神经母细胞瘤细胞的影响人体的神经母细胞瘤（ＮＢ）是来源于胚胎期神经嵴细胞，某些临床研究提示了ＮＢ是来源于......
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目的:观察针药结合对脑卒中肢体痉挛大鼠大脑皮质脑源性神经营养因子(brain-derived neurotrophic factor,BDNF)、酪氨酸蛋白激酶......
