目的　观察和评价诊断DIC的常用指标。方法　对 38例重症感染 (17例合并DIC)、2 3例急性白血病 (9例合并DIC)及 16例产科 (6例合并DIC)患者行凝血酶原时间 (PT)、活化部分凝血活酶时间(APTT)、纤维蛋白含量 (FIB)、血小板数量 (PLT)、D -二聚体 (D -D)、纤维蛋白 /纤维蛋白原降解产物 (FDP)、鱼精蛋白副凝试验 (3P试验 )检测。结果和结论　D -D及FDP敏感性高 ,但特异性较差 ,3P及FIB敏感性较低 ,但特异性较好 ,而PT的诊断率较高。但任一单项指标测定对DIC的诊断率均未超过 80 % ,而任意 3项以上指标的联合检测 ,诊断率可提高至 90 %以上 Objective To observe and evaluate the commonly used diagnostic criteria of DIC. Methods Thirty-eight patients with severe infection (17 with DIC), 23 with acute leukemia (9 with DIC) and 16 with obstetrics (6 with DIC) underwent thrombin time (PT), partial thromboplastin time (APTT), fibrin content (FIB), platelet count (PLT), D-dimer (D-D), fibrinogen / fibrinogen degradation product (FDP) Detection. RESULTS AND CONCLUSION D-D and FDP had high sensitivity but poor specificity, low sensitivity of 3P and FIB but good specificity and high diagnostic rate of PT. However, the diagnostic rate of DIC for any single index measurement did not exceed 80%, and any combination of three or more indicators, the diagnostic rate can be increased to more than 90%