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目的探讨米非司酮联合宫瘤清胶囊治疗子宫肌瘤的临床效果。方法选取2013年5月至2015年6月间海南省东方市人民医院收治的160例子宫肌瘤患者,采用随机数表法分为观察组与对照组,每组80例。观察组患者使用米非司酮联合宫瘤清胶囊治疗,对照组患者使用米非司酮治疗。比较两组患者不良反应发生率、子宫肌瘤体积变化情况和治疗效果。结果治疗后,观察组患者不良反应发生率为3.8%,低于对照组患者的15.0%,差异有统计学意义(P<0.05);观察组患者治疗后子宫肌瘤体积为(9.12±1.75)cm~3,小于对照组患者的(14.10±1.79)cm~3,差异有统计学意义(P<0.05);观察组患者总有效率为95.0%,高于对照组患者的75.0%,差异有统计学意义(P<0.05)。结论采用米非司酮联合宫瘤清胶囊治疗子宫肌瘤,可减轻不良反应,缩小患者肌瘤体积,改善临床症状,效果显著,值得推广。
Objective To investigate the clinical effect of mifepristone combined with Gongyuqing Capsule in the treatment of uterine fibroids. Methods Totally 160 patients with uterine fibroids who were treated in Dongfang People’s Hospital of Hainan Province from May 2013 to June 2015 were randomly divided into observation group and control group with 80 cases in each group. Patients in the observation group were treated with mifepristone combined with Gong Mi Qing Capsule, and patients in the control group were treated with mifepristone. The incidence of adverse reactions, changes in the volume of uterine fibroids and the therapeutic effect were compared between the two groups. Results After treatment, the incidence of adverse reactions in the observation group was 3.8%, which was lower than that in the control group (15.0%) (P <0.05). The volume of uterine fibroids in the observation group was (9.12 ± 1.75) cm ~ 3, less than the control group (14.10 ± 1.79) cm ~ 3, the difference was statistically significant (P <0.05). The total effective rate in the observation group was 95.0%, which was higher than that in the control group Statistical significance (P <0.05). Conclusions The use of mifepristone combined with Gongyuqing capsule in the treatment of uterine fibroids can reduce adverse reactions, reduce the volume of patients with fibroids, improve clinical symptoms, the effect is significant and worth promoting.