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Tumid lupus erythematosus (LE) is a relatively rare and only recently recogni zed subset of chronic cutaneous lupus. We report a case occuring in a male with HIV infection whereby his rash was only unmasked by immune restoration following highly active antiretroviral therapy (HAART). The phenomenon of latent inflamma tory or autoimmune disease appearing following HAART is now recognized as the “ immune restoration syndrome” and tumid LE has not been reported in this setti ng previously. Fortunately this variant of lupus does not result in scarring and is responsive to anti-malarials, allowing continuation of HAART in this patie nt.
Tumid lupus erythematosus (LE) is a relatively rare and only recently recognized subset of chronic cutaneous lupus. We report a case occuring in a male with HIV infection characterized his rash was only unmasked by immune restoration following highly active antiretroviral therapy (HAART). The phenomenon of latent inflammaory or autoimmune disease appearing following HAART is now recognized as the “immune restoration syndrome” and tumid LE has not been reported in this setti ng previously. Fortunately this variant of lupus does not result in scarring and is responsive to anti -malarials, may continuations of HAART in this patie nt.