1925年 Moschcowitz 第一次描述了1例以溶血性贫血、血小板减少性紫癜和飘忽不定的神经系统症状为特征的综合征。此后有关该综合征的报道和研究日渐增多,但各家命名不同,如 Moschcowitz 病或综合征、血栓性微血管病性溶血性贫血、血小板末梢血管血栓形成、血小板血栓形成综合征、溶血小板性血小板减少性紫癜等。直到1947年 Singer 将之正式命名为血栓性血小板减少性紫癜(thromboticthrombocytopenic purpura,TTP),为大多数学者所接受,且一直沿用至今。近年来,对于本病的病因、发病机理、病理、治疗等诸方面都有很广 For the first time in 1925 Moschcowitz described a syndrome characterized by hemolytic anemia, thrombocytopenic purpura and erratic neurological symptoms. Since then, there has been a growing number of reports and studies of this syndrome, but each has a different name, such as Moschcowitz’s disease or syndrome, thrombotic microangiopathic hemolytic anemia, peripheral platelet thrombosis, thrombotic thrombosis, thrombocytopenia Reduce purpura and so on. Until 1947 Singer formally named thrombotic thrombocytopenic purpura (thrombotic thrombocytopenic purpura, TTP), accepted by most scholars, and has been in use so far. In recent years, the etiology, pathogenesis, pathology, treatment and other aspects of this disease are very broad