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本发明公开了一种对于作为一种内皮脂肪酶抑制剂有效的化合物。其药物组成对内皮脂肪酶具有抑制作用,此脂肪酶可用式子表示:它是药物可接受盐或者溶剂化合物,其中A环是含氮的杂环,环A可用取代基或由下式的基团取代:-C(R1R2)-C(=
The present invention discloses a compound which is effective as an endothelase inhibitor. Its pharmaceutical composition has an inhibitory effect on endothelial lipase, which lipase may be represented by the formula: It is a pharmaceutically acceptable salt or a solvate wherein Ring A is a nitrogen-containing heterocycle and ring A may be substituted with a substituent The group replaces: -C (R1R2) -C (=