本文报导庆大霉素所致急性肾衰12例,男11例,女1,例年龄14—60岁,平均30岁。经透析综合治疗痊愈9例,死亡3例。庆大枚素进入人体后约90％经肾小球滤过,其中小部分在近曲管及直部被摄入肾小管细胞内。它在肾皮质中的浓度常高于血浆,半衰期也较长。故用药剂大,时间越长其皮质 This article reports 12 cases of acute renal failure caused by gentamicin, 11 males and 1 females, aged 14-60 years, average 30 years old. Hemodialysis comprehensive treatment recovered in 9 cases, 3 died. Approximately 90% of HGMs enter the human body through the glomerular filtration, a small part of which is in the proximal tubule and the straight portion is taken into the renal tubular cells. Its concentration in the renal cortex is often higher than the plasma, the half-life is also longer. Therefore, the use of drugs, the longer the cortex