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目的对台州地区未成年人呼吸道合胞病毒(RSV)感染进行监测,了解其流行特点。方法对2005年1月至2008年12月来浙江省台州医院就诊的呼吸道感染的患者3556名采集呼吸道分泌物,利用直接免疫荧光法进行RSV抗原检测。结果 2005-2008年的RSV阳性率分别为42.23%、20.24%、46.40%、22.16%。不同年度的RSV阳性率比较差异有统计学意义。RSV阳性率总体上从10-11月开始明显增高,持续到次年的3-4月,全年均有散发存在,但每年的流行趋势存在差别。3556例标本中,共有RSV阳性1281例,RSV阳性率为36.02%,RSV<1岁组1081例(30.40%),1～3岁组174例(4.89%),>3岁组26例(0.73%),各年龄组间检出率差异有统计学意义(P<0.01)。男性908例(35.75%),女性373例(36.71%),男女性差异无统计学意义(P>0.05)。结论 RSV是台州地区冬春季节引起小儿呼吸道感染的主要病毒,但RSV感染率存在年度差异。年龄越小RSV感染率越高,各年龄阶段的男性与女性对RSV同等易感。
Objective To monitor the infection of respiratory syncytial virus (RSV) in minors in Taizhou and to understand its epidemiological characteristics. Methods From January 2005 to December 2008, 3556 respiratory infections were collected from patients with respiratory tract infection in Taizhou Hospital of Zhejiang Province. RSV antigen was detected by direct immunofluorescence. Results The positive rates of RSV in 2005-2008 were 42.23%, 20.24%, 46.40% and 22.16% respectively. RSV positive rate in different years was significantly different. The positive rate of RSV generally increased significantly from October to November and continued to spread throughout the year from March to April of the next year, but there was a difference in the annual epidemic trend. Among 3556 cases, there were 1281 cases of RSV positive, the positive rate of RSV was 36.02%, 1081 cases (30.40%) in RSV <1 year old group, 174 cases (4.89%) in 1-3 years old group and 26 cases (> %), The detection rate of each age group was statistically significant (P <0.01). There were 908 males (35.75%) and 373 females (36.71%), there was no significant difference between males and females (P> 0.05). Conclusion RSV is the major virus causing respiratory tract infection in children in Taizhou in winter and spring. However, there are annual differences in RSV infection rate. The younger the RSV infection rate, the younger men and women of all ages are equally susceptible to RSV.