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目的了解盐城地区献血者戊型肝炎病毒感染情况,为制定献血者戊型肝炎筛查策略提供依据。方法用ELISA法检测献血者Ig M/Ig G抗-HEV,用荧光定量PCR技术检测献血者HEV RNA。结果 631名献血者抗-HEV检测未检出Ig M+/Ig G-者;检出Ig M+/Ig G+10例,阳性率为1.58%;检出Ig M-/Ig G+阳性241例,阳性率为38.19%;未检出HEV RNA阳性。结论 HEV在盐城地区献血人群中既往感染率较高,但是否对输血安全构成威胁还需进一步研究。
Objective To understand the status of hepatitis E virus infection among blood donors in Yancheng area and provide evidence for the development of hepatitis E screening test in blood donors. Methods The anti-HEV of Ig M / Ig G of blood donors was detected by ELISA and the HEV RNA of blood donors was detected by real-time fluorescence quantitative PCR. Results 631 blood donors did not detect Ig M + / Ig G- in anti-HEV test; 10 cases were Ig M + / Ig G + positive test, the positive rate was 1.58%; 241 cases were positive for Ig M- / Ig G + The rate was 38.19%; HEV RNA was not detected positive. Conclusion The prevalence rate of HEV in blood donors in Yancheng area is high. However, further study is needed to determine whether HEV poses a threat to blood transfusion safety.