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作者回顾性总结本院SICU1992年1月至1995年9月救治的229例普外危重症,平均年龄为57.87±16.12岁;男141例,女88例;APACHE-II积分10~33分,平均18.05±5.33分。主要原发病为胰腺疾病93例、肝胆疾病45例、胃肠和其他疾病69例、严重复合伤22例。其中腹腔感染119例和全身感染89例。器官合并症属呼吸系的115例、心血管91例、胃肠道37例、肾功能障碍30例、肝功障碍25例、出凝血障碍17例和中枢神经系障碍8例,其中MODS102例。通过改善氧代谢为目标的器官功能支持,把再手术清除感染灶作为遏制高分解代谢,恢复正氮平衡,防治MODS的重点措施。使病死率降为23.6%(54/229),比预计病死率(30.7%)降低7.1%。MODS病死率为49%(50/102)。
The authors retrospectively reviewed 229 cases of general critically ill critical illness treated in our hospital from January 1992 to September 1995, with an average age of 57.87 ± 16.12 years; 141 males and 88 females; and APACHE-II scores of 10 ~ 33 points, an average of 18.05 ± 5.33 points. The main primary disease was 93 cases of pancreatic disease, 45 cases of hepatobiliary disease, gastrointestinal and other diseases in 69 cases, 22 cases of severe combined injury. 119 cases of abdominal infection and systemic infection in 89 cases. Organ complications were 115 cases of respiratory system, 91 cases of cardiovascular, gastrointestinal tract in 37 cases, 30 cases of renal dysfunction, liver dysfunction in 25 cases, 17 cases of coagulation disorders and 8 cases of central nervous system disorders, of which 102 cases of MODS. Through the improvement of oxygen metabolism as the target of organ function support, the removal of infection by reoperation as a focal point to curb high catabolism, restore positive nitrogen balance, prevention and treatment of MODS. The mortality rate was reduced to 23.6% (54/229), which was 7.1% lower than the estimated case fatality rate (30.7%). MODS mortality was 49% (50/102).