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目的:探讨肝细胞癌的大小与边缘部 CT征象及有关病理基础的关系。方法:收集 45例经手术、病理证实的肝细胞癌,观察其大小与边缘部的 CT表现及有关的病理改变。结果:肝细胞癌的大小与其 CT边缘部的形态改变及瘤旁小门静脉癌栓的发生率无关。病理上瘤旁周围肝组织内癌细胞的浸润程度与肝细胞癌边缘部的形态有关,而与它的大小无关。结论:肝细胞癌本身的膨胀性或浸润性生长方式,是决定肿瘤边缘部形态的主要因素;在分析肝细胞癌侵犯门静脉是否发生癌栓时,不能单凭肿瘤的大小或只注意门静脉主干及左、右分支的改变,而更重要的是要对瘤旁小门静脉癌栓的观察;肝细胞癌边缘部 CT的形态改变,对于术前预测瘤旁周围肝细胞内癌细胞的浸润程度有较大的帮助。
Objective: To investigate the relationship between the size of hepatocellular carcinoma and the CT sign of the marginal region and the related pathological basis. Methods: Forty-five cases of hepatocellular carcinoma confirmed by surgery and pathology were collected. The CT appearances and related pathological changes in the size and margin were observed. RESULTS: The size of hepatocellular carcinoma was not related to the morphological changes at the CT edge and the incidence of paratumoral tumor thrombosis. Pathologically, the degree of infiltration of cancer cells in the liver tissue around the tumor is related to the morphology of the edge of hepatocellular carcinoma, but not its size. CONCLUSIONS: The dilated or invasive growth pattern of hepatocellular carcinoma itself is the main factor in determining the shape of the marginal region of the tumor; in the analysis of whether the hepatocellular carcinoma invades the portal vein, it is not possible to rely on the size of the tumor or only the trunk of the portal vein. Changes in the left and right branches, and more importantly, the observation of paraneoplastic portal vein tumor thrombi; the CT morphological changes at the edge of hepatocellular carcinoma are more predictive of preoperative invasion of cancer cells in the surrounding hepatocytes. Big help.