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目的了解前列腺增生(BPH)中前列腺上皮内瘤(PIN)的CT灌注成像表现,并初步探讨PIN与前列腺癌(PCa)及良性BPH的灌注成像表现的关系。资料与方法BPH25例,其中PIN样变9例,良性BPH 16例。PCa 34例,行前列腺病变中心层面灌注扫描,得到各组灌注图(PF)、强化峰值图(PEI)、达峰时间图(TTP)、血容量(BV)值和时间密度曲线(TDC),并对各组灌注值进行对比分析。结果PIN的PF值大于良性BPH,TTP值小于良性BPH,差异有统计学意义。PIN的TTP值大于PCa组,PF值小于PCa组,差异有统计学意义。结论PIN的CT灌注成像表现提示,PIN的PF值和TTP值与PCa和良性BPH不同,介于两者间。这种灌注特征可能为早期发现PCa提供一定帮助。
Objective To investigate the CT perfusion imaging of prostatic intraepithelial neoplasia (PIN) in benign prostatic hyperplasia (BPH) and to investigate the relationship between PIN and the perfusion imaging of prostate cancer (PCa) and benign prostatic hyperplasia (BPH). Materials and Methods 25 cases of BPH, including 9 cases of PIN-like changes, 16 cases of benign BPH. (PCa), perfusion scans of prostatic lesions were performed in 34 cases of PCa. Perfusion perfusion (PF), PEI, TTP, BV and TDC were obtained. The perfusion values of each group were compared and analyzed. Results The PF value of PIN was higher than that of benign BPH, and the value of TTP was lower than that of benign BPH. The difference was statistically significant. PIN TTP value is greater than PCa group, PF value is less than PCa group, the difference was statistically significant. Conclusions The CT perfusion imaging of PIN suggests that PF and TTP of PIN are different from those of PCa and benign BPH. This perfusion feature may provide some help in early detection of PCa.