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目的通过L-精氨酸治疗对胎儿生长受限的临床观察,探讨L-精氨酸对胎儿生长受限的治疗效果。方法将胎儿生长受限患者60例,随机分为常规治疗组(A组)30例,L-精氨酸治疗组(B组)30例,孕期定期用B型超声监测两组胎儿生长发育参数,产后比较新生儿出生体重和围产儿结局。结果生长参数:治疗后A组与B组比较,B组双顶径(BPD)、股骨长(FL)及腹围(AC)的增长幅度较高(P均<0.05)。新生儿出生体重和围产儿结局:B组的治愈率显著高于A组(P<0.05),新生儿平均出生体重高于A组,小于胎龄儿(SGA)的发生率低于A组。结论L-精氨酸治疗较常规治疗疗效更显著,能更好地增加胎儿体重促进胎儿发育。
Objective To investigate the therapeutic effect of L-arginine on fetal growth restriction by limiting the growth of fetus through L-arginine therapy. Methods 60 cases of fetal growth restriction were randomly divided into routine treatment group (A group) 30 cases, L-arginine treatment group (B group) 30 cases during pregnancy with regular B-mode ultrasound monitoring of fetal growth and development parameters Postnatal comparison of newborns birth weight and perinatal outcome. Results Growth parameters: The BPD, FL and AC of group B were higher than that of group B after treatment (P <0.05). Neonatal birth weight and perinatal outcome: The cure rate of group B was significantly higher than that of group A (P <0.05). The average birth weight of newborns was higher than that of group A, and the incidence of small gestational age (SGA) was lower than that of group A. Conclusion L-arginine treatment is more effective than conventional treatment, can better increase fetal body weight and promote fetal development.