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目的:观察急性呼吸衰竭采取纳洛酮与小剂量多巴胺、酚妥拉明联合用药的效果。方法:选取60例急性呼吸衰竭患者分为对照组和观察组各30例,对照组给予积极抗感染等常规治疗;观察组在常规治疗基础上给予纳洛酮与小剂量多巴胺、酚妥拉明联合治疗,观察两组治疗效果。结果:观察组总有效率为93.33%明显高于对照组76.67%,差异有统计学意义(P<0.05);治疗后两组PaO2、PaCO2、SaO2指标较治疗前有明显的改善,差异有统计学意义(P<0.05)。结论:急性呼吸衰竭采取纳洛酮与小剂量多巴胺、酚妥拉明联合用药是可行的,效果较显著。
Objective: To observe the effect of combining naloxone with low-dose dopamine and phentolamine in acute respiratory failure. Methods: Sixty patients with acute respiratory failure were divided into control group and observation group, 30 cases in each group. The control group was given active anti-infective and other routine treatment. The observation group was given naloxone with low dose of dopamine, phentolamine Combined treatment, observation of two groups treatment effect. Results: The total effective rate of the observation group was 93.33%, which was significantly higher than that of the control group (76.67%), the difference was statistically significant (P <0.05). The PaO2, PaCO2 and SaO2 indexes of the two groups were significantly improved after treatment Significance (P <0.05). Conclusion: The combination of naloxone with low-dose dopamine and phentolamine is feasible and effective in acute respiratory failure.