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目的:评价垂体后叶素联合碘仿纱条在宫颈冷刀锥形切除术中的止血效果。方法 :将该院宫颈上皮内瘤样变Ⅲ级行宫颈冷刀锥形切除术的患者80例按术中止血方法不同分2组,观察组(40例)术中宫颈注射垂体后叶素及术毕阴道填塞碘仿纱条;对照组(40例)术中生理盐水宫颈局部注射,术毕单纯纱布阴道填塞。比较两组术中出血量、需要缝合止血的例数、手术时间、术后出血例数、不良反应及手术并发症的发生率。结果:治疗组手术时间(35±4.8)min明显短于对照组手术时间(55±6.6)min,两组差异有统计学意义,P<0.05。术中出血量观察组(30.2±7.5)ml少于对照组(54±8.2)ml,两组差异有统计学意义,P<0.05。观察组术后出血量、阴道排液量明显较对照组少,创面愈合时间较对照组缩短,差异均有统计学意义(P<0.05),且观察组无药物不良反应及手术并发症发生。结论:垂体后叶素联合碘仿纱条在宫颈冷刀锥形切除术中止血效果好,出血量少,值得临床推广。
Objective: To evaluate the hemostatic effect of pituitrin combined with iodoform gauze in conization of cervical cold knife. Methods: 80 cases of cervical intraepithelial neoplasia grade Ⅲ cervical cold knife conization were divided into 2 groups according to the method of intraoperative hemostasis. The observation group (40 cases) intraoperative cervical injection of pituitrin and Intraoperative vaginal filling iodoform gauze; control group (40 cases) Intraoperative saline cervical injection, surgery completed gauze vaginal packing. Comparing the two groups of intraoperative bleeding, the need for suture hemostasis number, operation time, postoperative bleeding cases, adverse reactions and the incidence of surgical complications. Results: The operative time (35 ± 4.8) min in the treatment group was significantly shorter than that in the control group (55 ± 6.6) min, the difference was statistically significant (P <0.05). The intraoperative blood loss in the observation group (30.2 ± 7.5) ml less than the control group (54 ± 8.2) ml, the difference between the two groups was statistically significant, P <0.05. The amount of postoperative bleeding and vaginal discharge in the observation group was significantly less than that in the control group, and the wound healing time was shorter than that in the control group (P <0.05). No drug adverse reactions and complications occurred in the observation group. Conclusion: Pituitrin combined with iodoform gauze in the cold knife taper resection of cervical bleeding effect, less bleeding, it is worth clinical promotion.