本文研究Centoxin对革兰阴性杆菌菌血症和败血症的治疗效果。方法明确诊断的革兰阴性杆菌菌血症的住院患者543例,年龄≥18岁。症状有体温>38.3℃或<35.6℃,心动过速,呼吸急促,有全身中毒症状或周围循环灌注不良。进行随机、双盲、安慰剂对照试验。治疗组262例,安慰剂对照组281例,对99％的患者作了28天随访。治疗组给予本品100 mg,用人血白蛋白3.5 g稀释后静注,15～20分钟 This article studies the effect of Centoxin on Gram-negative bacilli and septicemia. Methods A total of 543 hospitalized patients with Gram-negative bacteremia were diagnosed, with a mean age of 18 years or older. Symptoms are body temperature> 38.3 ℃ or <35.6 ℃, tachycardia, shortness of breath, symptoms of systemic poisoning or poor peripheral perfusion. Randomized, double-blind, placebo-controlled trials. 262 patients in the treatment group and 281 patients in the placebo control group were followed up for 28 days in 99% of the patients. The treatment group given this product 100 mg, intravenous infusion of human serum albumin 3.5 g diluted, 15 to 20 minutes