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目的:分析乳酸清除率联合降钙素原(PCT)监测在55例脓毒症患者预后评价中的应用效果。方法:选取本院收治的55例脓毒症患者,监测患者入院时与入院6 h的静脉血乳酸及PCT等指标,分为低清除率组和高清除率组、低PCT组和高PCT组、存活组和死亡组,比较并分析乳酸清除率及PCT值的变化。结果:低PCT组的死亡率为22.6%,低于高PCT组的45.8%(P<0.05);低清除率组与高清除率组的死亡率分别为21.4%和53.8%,前者高于后者(P<0.05);死亡组入院时、入院6 h的血乳酸、PCT明显高于存活组(P<0.05),6 h乳酸清除率低于存活组,差异具有统计学意义(P<0.05)。结论:针对脓毒症患者进行乳酸清除率联合PCT测定,有利于判断患者的病情以及预后情况的判断。
Objective: To analyze the effect of lactic acid clearance combined with procalcitonin (PCT) monitoring in the prognosis evaluation of 55 sepsis patients. Methods: Seventy-five patients with sepsis admitted to our hospital were enrolled in this study. Intravenous blood lactate and PCT were monitored at admission and 6 h after admission. The patients were divided into two groups: low-clearance group, high-clearance group, low PCT group and high PCT group , Survival group and death group. The changes of lactic acid clearance and PCT value were compared and analyzed. Results: The mortality rate in the low PCT group was 22.6%, which was lower than that in the high PCT group (45.8%, P <0.05). The mortality rates in the low-clearance group and the high-clearance group were 21.4% and 53.8% (P <0.05). At the time of admission, the blood lactic acid and PCT at 6 h after admission were significantly higher than those in survivors (P <0.05), and the lactic acid clearance rates at 6 h were lower than those in survivors (P <0.05) ). Conclusion: The lactic acid clearance rate in patients with sepsis combined with PCT determination is helpful to judge the patient’s condition and prognosis.