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目的观察瑞舒伐他汀对老年糖尿病并颈动脉粥样硬化斑块疗效。方法将研究对象随机分为瑞舒伐他汀治疗组及辛伐他汀对照组,疗程24周,观察治疗前后颈动脉内膜-中层厚度、斑块总面积数、平均斑块数目、斑块积分的变化。结果治疗组内膜-中层厚度、斑块总面积数、斑块积分明显低于治疗前(P<0.05),并且较对照组有统计学差异(P<0.05)。结论瑞舒伐他汀可以明显改善老年糖尿病患者颈动脉粥样硬化的发展。
Objective To observe the effect of rosuvastatin on elderly diabetic patients with carotid atherosclerosis plaque. Methods The subjects were randomly divided into rosuvastatin treatment group and simvastatin control group. The course of treatment was 24 weeks. The carotid artery intima - media thickness, total plaque area, average plaque area, plaque score Variety. Results The intima - media thickness, total plaque area and plaque score in treatment group were significantly lower than those before treatment (P <0.05), and were significantly different from those in control group (P <0.05). Conclusion Rosuvastatin can significantly improve the development of carotid atherosclerosis in elderly diabetic patients.