口服胺碘酮(Am)能有效地抑制对常规抗心律失常药无效的室性心动过速(VT)或室颤(VF),但起效慢且对可致命的室性心律失常的治疗作用有限。急性心肌梗死(AMI)早期心肌细胞处于危险的电生理阶段,预防应用具有与剂量相关的负性肌力作用的抗心律失常药物可导致严重的、致命的心律失常如VF和VT,心功能也因心肌缺血而减退。Am具有扩张冠状动脉的作用,较大剂量对心脏泵功能无抑制作用,耐受性好。本文总结1978～1997年8例AMI伴早期原发VF病例,经非同步电除颤后出现VT,用Am静脉注射转为窦性心律成功经验和体会。 Oral amiodarone (Am) is effective in inhibiting ventricular tachycardia (VT) or ventricular fibrillation (VF), which is not effective against conventional antiarrhythmic drugs but with slow onset of action and therapeutic effect on lethal ventricular arrhythmias limited. Early myocardial infarction (AMI) Early myocardial cells are in a dangerous electrophysiological phase and preventing the use of anti-arrhythmic drugs with dose-dependent negative inotropic effects can lead to serious, fatal arrhythmias such as VF and VT, as well as cardiac function Decreased due to myocardial ischemia. Am has the role of dilation of coronary artery, a larger dose of cardiac pump function without inhibition, good tolerance. This article summarizes 8 cases of AMI with early primary VF from 1978 to 1997, VT after AMI, successful experience of converting into AMR with Am intravenous injection.