Cyclosporin相关论文
作者用硫唑嘌呤/强的松龙行长期免疫抑制治疗8例异体肾移植受者,因对硫唑嘌呤不能耐受,对强的松龙有严重副反应,改用环孢多肽(cyc......
不少肾移植术后患者,在采用常规免疫抑制剂治疗时,常引起骨髓抑制而发生外周血白细胞减少。此时,可短时改用环孢素A(cyclosporin ......
目的:研究环孢素A(cyclosporin,CsA)诱发的牙龈肥大与CsA浓度的关系。方法:通过CsA用药后32例药物性牙龈肥大患者和对照组同期应用......
对与Graves病(GD)相关的眼病和发生于无甲亢的患者的变异型(眼GD)尚无完全令人满意的治疗。因为可能涉及对眶内肌、泪腺和其他眼......
患者20岁,女性。体重下降,间歇性腹泻伴直肠出血6个月,钡餐造影诊断为广泛小肠克隆氏病,直肠活检证实有克隆氏病的肉芽肿。用强的......
Cyclosporin成功地用于器官移植后,试用这种有效的免疫抑制剂治疗自身免疫性疾病就有了强烈吸引力。事实上已有少数患者在接受Cyc......
最近有两份报告提出,对新近诊断的胰岛素依赖性糖尿病人使用环孢霉素(cyclosporin)于诊断后的第一年可能有疗效,能增加内源性胰岛......
环孢菌素A(cyclosporin A,CyA)是一种新型免疫抑制剂,1978年Calne首次应用于器官移植并获得成功。后经大量临床药理研究,证实本药......
在所有应用慢作用抗风湿药物的患者中,半数以上在2年内因其毒性或无效而停药。虽然最初的研究表明,每天应用5mg/kg 以上的环孢素(......
Autoimmune diseases characterized by activation of immune effector cells and damage of target organs are currently trea......
Treatment of Severe Aplastic Anemia by Immunosuppressor Anti-lymphocyte Globulin/Anti-thymus Globuli
Objective:To study the therapeutic effect of combined therapy with Chinese drugs and immunosuppressors, mainly anti-lymp......
亲环素A(cyclophilin A,CyPA)是一种在生物界广泛存在、高度保守的蛋白质,最初作为环孢素A(cyclosporin A,CsA)的细胞受体被发现。......
该研究回顾性分析了某院27例由于对环胞霉素A不能耐受或无效而使用他克莫司预防急性和慢性移植物抗宿主反应(GvHD)的患者......
目的观察环孢素联合泼尼松治疗膜性肾病的临床疗效及安全性,为临床治疗提供新选择。方法将符合入组标准的84例特发性膜性肾病患者......
目的了解风湿免疫疾病患者应用环孢素治疗过程中不良反应的发生情况及其特点。方法收集2013年1月至2014年12月因风湿免疫疾病在北......
目的研究环孢素对肾病综合征患者Scr水平的影响。方法收集2010年4月至2014年6月在广东省人民医院住院期间经肾穿刺活检术明确病理......
Beneficial effect of an antibody against interleukin-2 receptor(daclizumab) in an experimental model
AIM: To investigate the use of Daclizumab (Dmab) as an immunosuppressive agent in an experimental model of hepatocyte xe......
Objective: To analyze the regulation effect of MDR-1 gene in human breast cancer cell by the differentiating agents, sod......
目的:对体外培养的牙龈上皮细胞和成纤维细胞施加环孢素A(cyclosporin,CsA)刺激,应用免疫组化方法探讨CsA引发药物性牙龈过度生长(......
Inhibitory effect of cyclosporin A on the immunological rejection of rats with cerebral hemorrhage f
BACKGROUND: At present, it has been confirmed that immunological rejection exists in the cell transplantation in brain t......
作者采用随机、双盲、安慰剂对照、交叉方法评价了环孢霉素(cyclosporin)治疗皮质激素依赖性慢性严重哮喘的疗效。 30例慢性严重......
环胞霉素A(cyclosporin A,CS-A)是含有11个氨基酸的环肽,其中7个已甲基化,因而造成分子的高度疏水性。已发现C-S-A是一种强有力的......
AIM: To address the effect of heat-shock protein 90(HSP90) inhibitors on the release of the hepatitis C virus(HCV), a ce......
Transport and uptake characteristics of a new derivative of berberine(CPU-86017) by human intestinal
AIM: The characteristics of transepithelial transport and uptake of CPU-86017 {[7-(4-chlorbenzyl)-7,8,13,13α-tetrahydr......
环孢霉素A(cyclosporin A)系瑞士Sandoz公司科学家报道的一种免疫抑制剂。它在动物实验性器官移植中能显著地延长移植物的存活时......
环孢素A(cyclosporin A, CsA)是器官移植的新型免疫抑制剂,临床应用后引起中枢神经系统中毒,国外文献仅有少数报道.我院自1984年6......
在1969/70年,瑞士Sandoz股份有限公司对新抗生素的研究中发现一种真菌(Tolypocladium inflatum Gams)的代谢产物具有狭谱的抑制真......
作者用环孢素A(cyclosporin A,CyA)治疗大平并殖吸虫(P.ohirai)感染大鼠,并观察了不同感染时间给药后的结果。每鼠经口感染20条后......
作者综述了近年来有关器官移植病人的临床药物动力学(以下简称药动学)文献219篇。作者首先指出由于环孢素(cyclosporin)的使用及......
由于Tolypocladium inflatum可产生由11个氨基酸组成的环状肽类——环孢菌素,故在生物技术上甚为重要。环孢菌素A(cyclosporin或c......
6 四环素类doxycyclin多西环素;辉瑞(美);美国专利3200149(1965)。guamecycline呱甲环素;Societa Prodo Antibiotici;英国专利104......
本文调查了15株粘鞭菌属Gliomastixluzulae菌种产生环孢菌素C的能力。分离自中国11省15个不同地区的菌种在葡萄糖-麦芽汁-蛋白胨液体培养基中于24~26℃发酵10d。代谢产......
从真菌SIA-F4829(Gliomastixluzulae(Fuckel)MasonetHughes)的发酵液中,分离出一种具有抗真菌活性的化合物SIA-C4829A,经理化性质鉴别,证明SIA-C4829A与环孢菌素C同质。这是首次从半知菌亚门、丝孢纲、丛梗孢目......
Effect of intrathymic injection of allogene antigen on immune response to sciatic nerve transplantat
BACKGROUND: The latest researches demonstrate that intrathymic injection of MHC antigen which reaches a certain dosage (......
目的观察尾加压素Ⅱ(Urotensin Ⅱ,U Ⅱ)对心肌细胞肥大的效应。方法以体外培养的SD乳鼠心肌细胞为实验模型,分为正常对照组,单纯U......
Cytophagic Histiocytic Panniculitis with Encephaloclastic Changes:A Case Report and Literature Revie
Cytophagic histiocytic panniculitis (CHP) was first described by Winkelmann and Bowie in 1980.[1] It is a rare group of ......
Electrophysiological actions of cyclosporin A and tacrolimus on rat hippocampal CA1 pyramidal neuron
Aim:The aim of the present study was to investigate the electrophysiologicalactions of cyclosporin A (CsA) and tacrolim......
Early cyclosporin A treatment retards axonal degeneration in an experimental peripheral nerve inject
Injury to peripheral nerves during injections of therapeutic agents such as penicillin G potassium is common in developi......
应用0.5%环孢霉素A(cyclosporin A,CsA)滴眼治疗穿透性角膜移植术后发生免疫排斥患者16例(16只眼),治愈9只眼,好转6只眼,无效1只眼......
Cyclophilin A(CypA,encoded by PPIA)is a peptidyl-prolyl cis/trans isomerase(PPIase)that is expressed ubiquitously in all......
LocaltopicalcyclosporinAinthetreatmentofherpessimplexkeratitisMeiZheng,ArndHeiligenhausandK.PeterSteuhlBackgroundT-iymphocyte...
LocaltopicalcyclosporinAinthetreatmentofherpessimplexkeratitisMeiZheng, ArndHeiligenhausandK. PeterSteuhlBackground......
Objective: To investigate the clinical characteristics and to compare the effects of several therapies of Mooren’s cor......